The following study was a detailed review conducted by Scientists from Tufts University, USA and University of California, Santa Cruz, USA.
Scientists critically analyzed exhaustive literature on novel class of endogenous bioelectronic devices that are widely applicable in areas of Regenerative medicine and Drug discovery. The article highlights crucial advances in Bioelectronics in association with Computational medicine, Synthetic bioengineering. Study is published in iScience Journal, Cell Press Publishing Group.
Cell Press Publishing Group – iScience Journal (2019)
Endogenous Bioelectrics in Development, Regeneration, and Cancer: Drugs and Bioelectronic Devices as Electroceuticals for Regenerative Medicine
Abstract
A major frontier in the post-genomic era is the investigation of the control of coordinated growth and three-dimensional form. Dynamic remodeling of complex organs in regulative embryogenesis, regeneration, and cancer reveals that cells and tissues make decisions that implement complex anatomical outcomes. It is now essential to understand not only the genetics that specifies cellular hardware, but also the physiological software that implements tissue-level plasticity and robust morphogenesis. Here, we review recent discoveries about the endogenous mechanisms of bioelectrical communication among non-neural cells that enables them to cooperate in vivo. We discuss important advances in bioelectronics, as well as computational and pharmacological tools that are enabling the taming of biophysical controls toward applications in regenerative medicine and synthetic bioengineering.
Source:
iScience Journal (2019) – Cell Press Publishing Group
URL: https://www.cell.com/iscience/fulltext/S2589-0042(19)30473-0#%20
Citation:
Levin, M., J. Selberg, et al. “Endogenous Bioelectrics in Development, Regeneration, and Cancer: Drugs and Bioelectronic Devices as Electroceuticals for Regenerative Medicine.” Online Now, iScience. DOI: https://doi.org/10.1016/j.isci.2019.11.023
